Discordance for psoriatic arthropathy in monozygotic twins
نویسندگان
چکیده
منابع مشابه
Discordance for ankylosing spondylitis in monozygotic twins.
Three monozygotic twin pairs, each over the age of 45 years, with ankylosing spondylitis are described. In two pairs there is discordance for this disease and in the third pair there is a marked difference in the severity of this disease. These findings provide evidence that environmental factors are necessary not only for the initial development of ankylosing spondylitis, but possibly also for...
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A case of monozygotic male twins discordant for skeletal and cardiac defect is reported. One twin had the hemifacial microsomia type of the oculo-auriculo-vertebral dysplasia. The cotwin had no asymmetry of the face and normal ears, but preaxial polydactyly and ventricular and auricular septal defects. The cotwins were concordant for craniostenosis with a ridge metopic suture. Karyotypes were n...
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Discordance for childhood coeliac disease in monozygotic twin boys is reported. The diagnosis of coeliac disease in the second-born twin was established by demonstration of a flat small intestinal mucosa on biopsy and a clinical response to a gluten-free diet. The first-born twin had a normal small intestinal mucosa. Phenotypic, genotypic, and dermatoglyphic observations as well as gross observ...
متن کاملCyclosporine in psoriatic arthropathy.
Psoriatic arthropathy (PsA) is an inflammatory arthropathy associated with skin or nail psoriasis with heterogeneous clinical manifestations. A pragmatic therapeutic approach to PsA is to stratify the disease manifestations according to their response to synthetic and biological agents. It is now reasonably well established that peripheral arthritis is amenable to treatment with synthetic disea...
متن کاملPsoriatic arthropathy: where now?
P soriatic arthropathy is a common inflammatory arthritis that characteristically occurs in individuals with psoriasis [1]. PsA was classified as a distinct entity for the first time in 1964 [2], but the antiquity of this disease can be dated back tens of centuries [3]. The many faces of PsA have historically complicated the timely diagnosis on the one hand, while its aggressive and destructive...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1979
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780220723